Prevalence of enuresis and its impact in quality of life of patients with sickle cell disease

Vol. 45 (x): 2019 August 8.[Ahead of print]

doi: 10.1590/S1677-5538.IBJU.2019.0026


ORIGINAL ARTICLE

Alana de Medeiros Nelli 1, Flávia Cristina de Carvalho Mrad 2, Mateus de Andrade Alvaia 1, Heros Aureliano Antunes da Silva Maia 1, Carina Oliveira Silva Guimarães 3, Evanilda Souza de Santana Carvalho 3, Cristiano Mendes Gomes 3, José Murillo Bastos Netto 4,5,6, José de Bessa Junior 1,3
1 Departamento de Cirurgia Universidade Estadual de Feira de Santana, Feira de Santana, BA, Brasil; 2 Departamento de Pediatria, Unidade de Nefrologia Pediátrica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.; 3 Programa de Pós-Graduação em Saúde Coeltiva, Universidade Federal de Juiz de Fora, Juiz de For a, MG, Brasil; 4 Departamento de Cirurgia, Faculdade de Ciências Médicas e da Saúde de Juiz de Fora; 5 Faculdade de Ciências Médicas e da Saúde de Juiz de Fora, MG, Brasil; 6 Hospital e Maternidade Terezinha de Jesus de Juiz de Fora, Juiz de Fora, MG, Brasil

 ABSTRACT

Introduction: Evidence indicates an increase in the prevalence of enuresis in individu-als with sickle cell disease. The present study aims to evaluate the prevalence and im- pact of enuresis on quality of life in individuals with sickle cell disease. Materials and Methods: This cross-sectional study evaluated individuals with sickle cell disease followed at a reference clinic, using a questionnaire designed to evaluate the age of complete toilet training, the presence of enuresis and lower urinary tract, and the impact on quality of life of these individuals. Results: Fifty children presenting SCD (52% females, mean age ten years) were in-cluded in the study. Of those, 34% (17/50) presented as HbSC, 56% with HbSS (28/50), 2% S_-thalassemia (1/5) and 8% the type of SCD was not determined. The prevalence of enuresis was 42% (21/50), affecting 75% of subjects at fi ve years and about 15% of adolescents at 15 years of age. Enuresis was classifi ed as monosymptomatic in 33.3% (7/21) and nonmonosymptomatic in 66.6% (14/21) of the cases, being primary in all subjects. Nocturia was identifi ed in 24% (12/50), urgency in 20% (10/50) and daytime incontinence 10% (5/50) of the individuals. Enuresis had a signifi cant impact on the quality of life of 67% of the individuals. Conclusion: Enuresis was highly prevalent among children with SCD, and continues to be prevalent throughout early adulthood, being more common in males. Primary nonmonosymptomatic enuresis was the most common type, and 2/3 of the study popu-lation had a low quality of life.

Keywords: Quality of Life; Sickle Cell Trait; Enuresis

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