International Brazilian Journal of Urology https://www.intbrazjurol.com.br Tue, 20 Aug 2019 17:19:50 +0000 en-US hourly 1 https://wordpress.org/?v=5.2.2 https://www.intbrazjurol.com.br/wp-content/uploads/2016/02/cropped-fav_icon_ibju-32x32.jpg International Brazilian Journal of Urology https://www.intbrazjurol.com.br 32 32 Editorial Comment: Study of kidney morphologic and structural changes related to different ischemia times and types of clamping of the renal vascular pedicle https://www.intbrazjurol.com.br/editorial/editorial-comment-study-of-kidney-morphologic-and-structural-changes-related-to-different-ischemia-times-and-types-of-clamping-of-the-renal-vascular-pedicle/ Tue, 20 Aug 2019 17:19:50 +0000 https://www.intbrazjurol.com.br/?p=8848 Vol. 45 (4): 763-764, July – August, 2019

doi: 10.1590/S1677-5538.IBJU.2018.0559.1


EDITORIAL

Luciano A. Favorito 1, 2, 3
1 Professor Titular, Unidade Urogenital da Univ. Est. do Rio de Janeiro – UERJ, RJ, Brasil; 2 Urologista do Hospital da Lagoa Federal, Rio de Janeiro , RJ, Brasil; 3 Editor Associado do International Braz J Urol

ABSTRACT

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Editorial Comment: External validation of nomogram to predict inguinal lymph node metastasis in patients with penile cancer and clinically negative lymph nodes https://www.intbrazjurol.com.br/editorial/editorial-comment-external-validation-of-nomogram-to-predict-inguinal-lymph-node-metastasis-in-patients-with-penile-cancer-and-clinically-negative-lymph-nodes/ Tue, 20 Aug 2019 16:59:18 +0000 https://www.intbrazjurol.com.br/?p=8833 Vol. 45 (4): 679-680, July – August, 2019

doi: 10.1590/S1677-5538.IBJU.2018.0756.1


EDITORIAL

Luciano A. Favorito 1, 2, 3
1 Professor Titular, Unidade Urogenital da Univ. Est. do Rio de Janeiro – UERJ, RJ, Brasil; 2 Urologista do Hospital da Lagoa Federal, Rio de Janeiro , RJ, Brasil; 3 Editor Associado do International Braz J Urol

ABSTRACT

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A comprehensive literature-based equation to compare cost-effectiveness of a flexible ureteroscopy program with single-use versus reusable devices https://www.intbrazjurol.com.br/review-article/a-comprehensive-literature-based-equation-to-compare-cost-effectiveness-of-a-flexible-ureteroscopy-program-with-single-use-versus-reusable-devices/ Tue, 20 Aug 2019 16:49:38 +0000 https://www.intbrazjurol.com.br/?p=8829 Vol. 45 (4): 658-670, July – August, 2019

doi: 10.1590/S1677-5538.IBJU.2018.0880


REVIEW ARTICLE

Giovanni S. Marchini 1,2, Fabio C. Torricelli 1,2, Carlos A. Batagello 1,2, Manoj Monga 1,2, Fabio C. Vicentini 1, Alexandre Danilovic 1, Miguel Srougi 1, William C. Nahas 1, Eduardo Mazzucchi 1
1 Seção de Endourologia da Divisão de Urologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP, Brasil; 2 Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, United States

ABSTRACT 

Purpose: to critically review all literature concerning the cost-effectiveness of flexible ureteroscopy comparing single-use with reusable scopes.

Materials and Methods: A systematic online literature review was performed in PubMed, Embase and Google Scholar databases. All factors potentially affecting surgical costs or clinical outcomes were considered. Prospective assessments, case control and case series studies were included.

Results: 741 studies were found. Of those, 18 were duplicated and 77 were not related to urology procedures. Of the remaining 646 studies, 59 were considered of relevance and selected for further analysis. Stone free and complication rates were similar between single-use and reusable scopes. Operative time was in average 20% shorter with digital scopes, single-use or not. Reusable digital scopes seem to last longer than optic ones, though scope longevity is very variable worldwide. New scopes usually last four times more than refurbished ones and single-use ureterorenoscopes have good resilience throughout long cases. Longer scope longevity is achieved with Cidex and if a dedicated nurse takes care of the sterilization process. The main surgical factors that negatively impact device longevity are lower pole pathologies, large stone burden and non-use of a ureteral access sheath. We have built a comprehensive fi nancial costeffective decision model to fl exible ureteroscope acquisition.

Conclusions: The cost-effectiveness of a fl exible ureteroscopy program is dependent of several aspects. We have developed a equation to allow a literature-based and adaptable decision model to every interested stakeholder. Disposable devices are already a reality and will progressively become the standard as manufacturing price falls.

Keywords: Cost-Benefi t Analysis; Ureteroscopy; Kidney Calculi

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Enhanced recovery after surgery (ERAS) in radical cystectomy patients: from consensus to evidences https://www.intbrazjurol.com.br/editorial/enhanced-recovery-after-surgery-eras-in-radical-cystectomy-patients-from-consensus-to-evidences/ Tue, 20 Aug 2019 16:44:36 +0000 https://www.intbrazjurol.com.br/?p=8827 Vol. 45 (4): 655-657, July – August, 2019

doi: 10.1590/S1677-5538.IBJU.2019.04.02


EDITORIAL

Marco Moschini 1,2, Armando Stabile 1,3, Agostino Mattei 2, Francesco Montorsi 3, Xavier Cathelineau 1, Rafael Sanchez-Salas 1

1 Department of Urology, L’Institut Mutualiste Montsouris, Université Paris Descartes, Paris, France; 2 Department of Urology, Luzerner Kantonsspital, Spitalstrasse, 6000 Luzern, Switzerland; 3 Department of Urology, Urological Research Institute, San Raffaele Scientific Institute, Milan, Italy

Bladder cancer (BCa) is the second most common genitourinary malignancy with 81,190 estimated new diagnoses for 2018 in the United States alone (1). Radical cystectomy (RC) with bilateral pelvic lymph node dissection (PLND) and perioperative chemotherapy is the standard treatment recurrent high risk non-muscle invasive and for muscle invasive BCa (2). However, RC as well as perioperative chemotherapy represent a complex procedure associated with high perioperative morbidity and mortality as a consequence also of the characteristics of the population which is generally affected by multiple comorbidities when compared to other surgical procedures (3, 4).

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Age and Body Mass Index: the most important factors of urinary and erectile function recovery after robotic assisted radical prostatectomy https://www.intbrazjurol.com.br/editorial/age-and-body-mass-index-the-most-important-factors-of-urinary-and-erectile-function-recovery-after-robotic-assisted-radical-prostatectomy/ Tue, 20 Aug 2019 16:41:34 +0000 https://www.intbrazjurol.com.br/?p=8825 Vol. 45 (4): 653-654, July – August, 2019

doi: 10.1590/S1677-5538.IBJU.2019.04.01


EDITORIAL In this issue

Luciano Alves Favorito 1, 2, 3
1 Unidade de Pesquisa Urogenital da Univ. Estadual do Rio de Janeiro – UERJ, Rio de Janeiro, RJ, Brasil; 2 Hospital Federal da Lagoa, Rio de Janeiro, RJ, Brasil; 3 Editor Associado da International Braz J Urol

The July-August 2019 issue of the International Brazilian Journal of Urology presents original contributions with a lot of interesting papers in different fields: Infertility, Bladder augmentation, Bladder Cancer, PCNL, Prostate Cancer, Renal Cell Carcinoma, Partial nephrectomy, Renal stones, Nocturnal Enuresis, Basic Research, Laparoscopic Surgery, Penile Cancer, Stress Urinary Incontinence and Adrenalectomy. The papers come from many different countries such as Italy, Brazil, USA, UK, Turkey, China, France, Iran, Republic of Korea, Argentina, India and Spain, and as usual the editor´s comment highlights some papers. We decided to comment the paper about a very interesting topic: Robotic-Assisted Radical Prostatectomy (RARP).

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XXXVII Congresso Brasileiro de Urologia – 2019 https://www.intbrazjurol.com.br/supplements/xxxvii-congresso-brasileiro-de-urologia-2019/ Mon, 19 Aug 2019 19:25:28 +0000 https://www.intbrazjurol.com.br/?p=8810 XXXVII Congresso Brasileiro de Urologia – 2019
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XXXIV Congresso Brasileiro de Urologia – 2013 https://www.intbrazjurol.com.br/supplements/xxxiv-congresso-brasileiro-de-urologia-2013/ Mon, 19 Aug 2019 19:15:31 +0000 https://www.intbrazjurol.com.br/?p=8807 XXXIV Congresso Brasileiro de Urologia – 2013
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Association between calcitonin receptor gene polymorphisms and calcium stone urolithiasis: A meta-analysis https://www.intbrazjurol.com.br/original-article/association-between-calcitonin-receptor-gene-polymorphisms-and-calcium-stone-urolithiasis-a-meta-analysis/ Thu, 15 Aug 2019 18:19:08 +0000 https://www.intbrazjurol.com.br/?p=8805 Vol. 45 (x): 2019 August 8.[Ahead of print]

doi: 10.1590/S1677-5538.IBJU.2019.0061


ORIGINAL ARTICLE


Jiaxuan Qin 1, Zonglong Cai 2, Jinchun Xing 1, Bo Duan 1, Peide Bai 1
1 Department of Urology Surgery, the First Affiliated Hospital of Xiamen University; Center of Diagnosis and Treatment of Urinary System Diseases, the First Affiliated Hospital of Xiamen University; the Key Laboratory of Urinary Tract Tumors and Calculi of Xiamen City, the First Affiliated Hospital of Xiamen University. Xiamen, Fujian, China; 2 The First Clinical Medical School of Fujian Medical University. Xiamen, Fujian, China

ABSTRACT

Purpose: It has been reported that calcitonin receptor (CALCR) gene polymorphisms might be associated with calcium stone urolithiasis. Owing to mixed and inconclusive results, we conducted a meta-analysis to summarize and clarify this association.
Materials and Methods: A systematic search of studies on the association between CALCR gene polymorphisms and calcium stone urolithiasis susceptibility was con-ducted in databases.
Results: Odds ratios and 95% confi dence intervals were used to pool the effect size. Five articles were included in our meta-analysis.
Conclusions: CALCR rs1801197 might be associated with increased risk of calcium stone urolithiasis. There is insuffi cient data to fully confi rm the association between CALCR rs1042138 and calcium stone urolithiasis susceptibility. Well-designed studies with larger sample size and more subgroups are required to validate the risk identifi ed in the current meta-analysis.

Keywords: Receptors, Calcitonin; Urolithiasis; Meta-Analysis [Publication Type]

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Prevalence of enuresis and its impact in quality of life of patients with sickle cell disease https://www.intbrazjurol.com.br/original-article/prevalence-of-enuresis-and-its-impact-in-quality-of-life-of-patients-with-sickle-cell-disease/ Thu, 15 Aug 2019 18:13:50 +0000 https://www.intbrazjurol.com.br/?p=8802 Vol. 45 (x): 2019 August 8.[Ahead of print]

doi: 10.1590/S1677-5538.IBJU.2019.0026


ORIGINAL ARTICLE

Alana de Medeiros Nelli 1, Flávia Cristina de Carvalho Mrad 2, Mateus de Andrade Alvaia 1, Heros Aureliano Antunes da Silva Maia 1, Carina Oliveira Silva Guimarães 3, Evanilda Souza de Santana Carvalho 3, Cristiano Mendes Gomes 3, José Murillo Bastos Netto 4,5,6, José de Bessa Junior 1,3
1 Departamento de Cirurgia Universidade Estadual de Feira de Santana, Feira de Santana, BA, Brasil; 2 Departamento de Pediatria, Unidade de Nefrologia Pediátrica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.; 3 Programa de Pós-Graduação em Saúde Coeltiva, Universidade Federal de Juiz de Fora, Juiz de For a, MG, Brasil; 4 Departamento de Cirurgia, Faculdade de Ciências Médicas e da Saúde de Juiz de Fora; 5 Faculdade de Ciências Médicas e da Saúde de Juiz de Fora, MG, Brasil; 6 Hospital e Maternidade Terezinha de Jesus de Juiz de Fora, Juiz de Fora, MG, Brasil

 ABSTRACT

Introduction: Evidence indicates an increase in the prevalence of enuresis in individu-als with sickle cell disease. The present study aims to evaluate the prevalence and im- pact of enuresis on quality of life in individuals with sickle cell disease. Materials and Methods: This cross-sectional study evaluated individuals with sickle cell disease followed at a reference clinic, using a questionnaire designed to evaluate the age of complete toilet training, the presence of enuresis and lower urinary tract, and the impact on quality of life of these individuals. Results: Fifty children presenting SCD (52% females, mean age ten years) were in-cluded in the study. Of those, 34% (17/50) presented as HbSC, 56% with HbSS (28/50), 2% S_-thalassemia (1/5) and 8% the type of SCD was not determined. The prevalence of enuresis was 42% (21/50), affecting 75% of subjects at fi ve years and about 15% of adolescents at 15 years of age. Enuresis was classifi ed as monosymptomatic in 33.3% (7/21) and nonmonosymptomatic in 66.6% (14/21) of the cases, being primary in all subjects. Nocturia was identifi ed in 24% (12/50), urgency in 20% (10/50) and daytime incontinence 10% (5/50) of the individuals. Enuresis had a signifi cant impact on the quality of life of 67% of the individuals. Conclusion: Enuresis was highly prevalent among children with SCD, and continues to be prevalent throughout early adulthood, being more common in males. Primary nonmonosymptomatic enuresis was the most common type, and 2/3 of the study popu-lation had a low quality of life.

Keywords: Quality of Life; Sickle Cell Trait; Enuresis

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Improvement of fertility parameters with tribulus terrestris and Anacyclus Pyrethrum treatment in male rats https://www.intbrazjurol.com.br/original-article/improvement-of-fertility-parameters-with-tribulus-terrestris-and-anacyclus-pyrethrum-treatment-in-male-rats/ Thu, 15 Aug 2019 18:01:57 +0000 https://www.intbrazjurol.com.br/?p=8800 Vol. 45 (x): 2019 August 8.[Ahead of print]

doi: 10.1590/S1677-5538.IBJU.2018.0843


ORIGINAL ARTICLE

Dariush Haghmorad 1,2, Mohammad Bagher Mahmoudi 3, Pardis Haghighi 4, Paria Alidadiani 4, Ensieh Shahvazian 4, Parsova Tavasolian 4, Mahmoud Hosseini 5, Mahmoud Mahmoudi 4
1 Department of Pathology and Laboratory Medicine, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran; 2 Department of Immunology, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran; 3 Department of Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 4 Immunology Research Center, BuAli Research Institute, Department of Immunology and Allergy, School of Medicine, Mashhad University of Medical Sciences; 5 Neuroscience Research Center, Department of Physiology, School of Medicine, Mashhad University of Medical Sciences

ABSTRACT

Objective: Anacyclus Pyrethrum (AP) and Tribulus Terrestris (TT) have been reported as male infertility treatment in several studies; however, in Iranian traditional medicine these two plants are prescribed simultaneously. In this study, we aimed to determine the effects of AP and TT extracts both separately and simultaneously on the male Wi-star rat fertility parameters. Materials and Methods: 32 male Wistar rats were divided into 4 groups: Control, TT, AP, and AT treated groups. Treatment continued for 25 days and rats were weighed daily. Their testes were dissected for histological studies. Sperm analysis including sperm count, viability and motility were performed. Serum was obtained to evaluate testosterone, LH and FSH levels. Histological studies were conducted to study Leydig, and Sertoli cells, spermatogonia and spermatid cell numbers, and to measure seminif-erous diameter and epithelium thickness. Results: Sperm count increased in all the treatment groups. Sperm viability and mo-tility in AT and AP groups were elevated. TT and AT groups showed signifi cantly increased testosterone level compared to control group (P=004, P=0.000, respectively) and TT, AP and AT treatment groups showed increased LH level (P=0.002, P=0.03 and P=0.000, respectively) compared to control, while only AT group showed increased FSH (p=0.006) compared to control. Histological studies showed signifi cant increase of spermatogonia, Leydig and Sertoli cell numbers and epithelial thickness in AT group compared to other groups. All the treatment groups had higher number of Leydig, spermatogonia and spermatid cells. Conclusion: TT and AP improved sexual parameters; however, their simultaneous ad- ministration had higher improving effects on studied parameters.

Keywords: Tribulus; Testosterone; Receptors, FSH; Receptors, LH

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